Published 1989 | Version v1
Journal article Metadata-only

The efficacies of pure LICAM(C) and DTPA for enhancing the elimination of plutonium-238 and americium-241 from rats after their inhalation as nitrate

Creators

  • 1. National Radiological Protection Board, Chilton (UK)

Description

After the inhalation of 238Pu and 241Am as nitrate, the repeated administration of DTPA is far superior to that of LICAM(C) for enhancing their elimination from the body. The therapeutic efficacies of these chelating agents are however similar after intravenous injection of 238Pu as citrate. It is concluded that DTPA should remain the agent of choice for treating persons contaminated internally with transportable forms of these actinides. (author)

Additional details

Publishing Information

Journal Title
Experimental Pathology (Jena)
Journal Volume
37
Journal Issue
1-4
Series
Exp. Pathol. (Jena).
Journal Page Range
83-88
ISSN
0232-1513
CODEN
EXPAD

Conference

Title
International symposium on inhalation toxicology.
Dates
19-24 Feb 1989.
Place
Hannover (Germany, F.R.).

INIS

Country of Publication
Germany
Country of Input or Organization
German Democratic Republic
INIS RN
21058314
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
AMERICIUM 241; DTPA; EXCRETION; FECES; INHALATION; PLUTONIUM 238; RADIONUCLIDE KINETICS; RADIOPROTECTIVE SUBSTANCES; RATS; TISSUE DISTRIBUTION; URINE
Descriptors DEC
ACTINIDE NUCLEI; ALPHA DECAY RADIOISOTOPES; AMERICIUM ISOTOPES; AMINO ACIDS; ANIMALS; BIOLOGICAL MATERIALS; BIOLOGICAL WASTES; BODY FLUIDS; CARBOXYLIC ACIDS; CHELATING AGENTS; CLEARANCE; DISTRIBUTION; DRUGS; EVEN-EVEN NUCLEI; HEAVY ION DECAY RADIOISOTOPES; HEAVY NUCLEI; INTAKE; ISOTOPES; KINETICS; MAMMALS; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; PLUTONIUM ISOTOPES; RADIOISOTOPES; RESPONSE MODIFYING FACTORS; RODENTS; SILICON 32 DECAY RADIOISOTOPES; SPONTANEOUS FISSION RADIOISOTO; VERTEBRATES; WASTES; YEARS LIVING RADIOISOTOPES