Published 1992 | Version v1
Book

Differential DNA damage, can we measure it, can we model it?

Creators

  • 1. California Univ., San Diego, La Jolla, CA (United States). Dept. of Radiology

Description

Differential DNA damage has three levels of complexity; number of lesions per site, identity of lesions, and distances apart of individual lesions. Modelling of such damage is severely limited by the lack of information on parameters of damage induction. Measurement of damage will be difficult in DNA extracted from irradiated cells, while it may be accomplished by use of a valid model system. (author)

Additional details

Publishing Information

Publisher
Adam Hilger.
Imprint Place
Bristol (United Kingdom)
ISBN
0-7503-0187-2
Imprint Title
Biophysical modelling of radiation effects
Imprint Pagination
360 p.
Journal Page Range
p. 323-326.

Conference

Title
Workshop on biophysical modelling of radiation effects.
Dates
2-5 Sep 1991.
Place
Padua (Italy).

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
24032567
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
DNA; GENETIC RADIATION EFFECTS; MATHEMATICAL MODELS
Descriptors DEC
BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; GENETIC EFFECTS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RADIATION EFFECTS

Optional Information

Contract/Grant/Project number
Grant NCI CA26279; NCI CA46295; DE-FG0388ER60660
Secondary number(s)
EUR--13848-EN.