Published April 2003 | Version v1
Report Metadata-only

Study of DNA structural mutation induced by heavy charged particles in malignant cells and normal epithelial cell lines

Creators

  • 1. Chiba Univ. (Japan). Graduate School of Medicine
  • 2. National Inst. of Radiological Sciences, Chiba (Japan). Research Center for Charged Particle Therapy
  • 3. Tokyo Dental Coll., Chiba (Japan). Chiba Hospital

Description

We evaluated DNA damages and RNA expressions in malignant tumor cells and normal epithelial cell lines which were irradiated by X-ray and heavy charged particles. As a result, the variety of DNA damages and RNA expressions were detected in several cell lines irradiated by several radiations. These results may support the outcome of clinical trials in heavy charged particles. (author)

Part of:
2002 annual report of the research project with heavy ions at NIRS-HIMAC

Additional details

Publishing Information

Imprint Title
2002 annual report of the research project with heavy ions at NIRS-HIMAC
Imprint Pagination
335 p.
Journal Page Range
p. 170-173
Report number
NIRS-M--166

INIS

Country of Publication
Japan
Country of Input or Organization
Japan
INIS RN
35044449
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Non-conventional Literature
Descriptors DEI
CARBON IONS; DNA DAMAGES; GENETIC RADIATION EFFECTS; HOURLY VARIATIONS; MELANOMAS; NEON IONS; RNA; SILICON IONS; SURVIVAL CURVES; TUMOR CELLS; VIABILITY; X RADIATION
Descriptors DEC
ANIMAL CELLS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; CARCINOMAS; CHARGED PARTICLES; DISEASES; ELECTROMAGNETIC RADIATION; EPITHELIOMAS; GENETIC EFFECTS; IONIZING RADIATIONS; IONS; NEOPLASMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; RADIATION EFFECTS; RADIATIONS; VARIATIONS

Optional Information

Secondary number(s)
HIMAC--069