Published September 1981 | Version v1
Journal article Metadata-only

Lung scanning and clearance of inhaled radiogold (198Au) particles in three patients with microlithiasis

Creators

  • 1. Bari Univ. (Italy). Cattedra di Medicina Nucleare
  • 2. Bari Univ. (Italy). Cattedra di Patologia Medica 2

Description

Lung clearance of inhaled radiogold (198Au) particles was evaluated in three siblings with alveolar microlithiasis. A significantly slower clearance was found in such patients as compared with normal controls. The pattern of serial scans clearly indicated the lung mucociliary function to be impaired. It is suggested that slowing of the clearance may represent a pathogenetic factor capable of favouring the formation of alveolar microliths. (orig.)

Abstract (German)

Bei drei Geschwistern mit alveolarer Mikrolithiase wurde die Radiogold-Clearance der Lunge nach Inhalation der Radiogoldteilchen szintigraphisch bestimmt. Wir stellten eine signifikant langsamere Clearance, verglichen mit normalen Probanden, fest. Wiederholte szintigraphische Untersuchungen ergaben eine einndeutige Beeintraechtigung der Flimmerepithelfunktion in der Lunge. Es ist anzunehmen, dass eine verlangsamte Clearance als pathogener Faktor beguenstigend auf die Bildung alveolarer Mikrolithe wirkt. (orig.)

Additional details

Publishing Information

Journal Title
Fortschr. Geb. Roentgenstr. Nuklearmed.
Journal Volume
135
Journal Issue
3
Series
Fortschr. Geb. Roentgenstr. Nuklearmed.
Journal Page Range
296-300
ISSN
0015-8151

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
13675382
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE; S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BIOMEDICAL RADIOGRAPHY; CALCULI; COLLOIDS; DIAGNOSIS; EPITHELIUM; GOLD 198; IMAGES; INHALATION; LUNG CLEARANCE; LUNGS; MUCOUS MEMBRANES; PATIENTS; RADIONUCLIDE ADMINISTRATION; SCINTISCANNING
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CLEARANCE; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISPERSIONS; EXCRETION; GOLD ISOTOPES; HEAVY NUCLEI; INTAKE; ISOTOPES; MEDICINE; NUCLEI; ODD-ODD NUCLEI; ORGANS; RADIOISOTOPE SCANNING; RADIOISOTOPES; RESPIRATORY SYSTEM; TISSUES