Published 1968
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Studies on the transformation of fibrinogen to fibrin. Radiation effects. Observation by electron microscopy
Creators
- 1. Commissariat a l'Energie Atomique, Grenoble (France). Centre d'Etudes Nucleaires
Description
The authors used electron microscopy, thrombo-dynamo-graphy and spectrophotometry, to study the damage caused by X rays on the fibrinogen molecule and fibrin-formation process. This process is highly disturbed by increasing doses of irradiation from 0 to 3.105 roentgen. Electron microscopy observation shows interesting data on the structure of the plug, formed by irradiated fibrinogen solution. This study also lead the authors to propose a new model of the fibrinogen molecule and a schema explaining observed striations and granular appearance of the fibrin fibers surface. (authors)
Availability note (English)
Available from INIS in electronic formAbstract (French)
Les auteurs ont utilise la microscopic electronique, la thrombodynamographie et la spectrophotometrie pour etudier l'action des rayons X sur la molecule de fibrinogene et sur le processus de la fibrino-formation. Ce processus est fortement altere lorsqu'on augmente les doses d'irradiation de 0 a 3.105 roentgen. La microscopic electronique a donne des resultats interessants sur la structure du caillot forme a partir de solution de fibrinogene irradie. Cette etude a permis egalement aux auteurs de proposer un nouveau modele pour la molecule de fibrinogene et un schema expliquant les situations observees sur les fibres de fibrine. (auteurs)Files
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Additional details
Additional titles
- Original title (French)
- Etude de la transformation du fibrinogene en fibrine. Effet des radiations ionisantes. Observation en microscopie electronique
Publishing Information
- Imprint Pagination
- [22 p.]
- Report number
- CEA-R--3539
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 35091378
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; ELECTRON MICROSCOPY; FIBRIN; FIBRINOGEN; X RADIATION
- Descriptors DEC
- BIOLOGICAL EFFECTS; BLOOD COAGULATION FACTORS; ELECTROMAGNETIC RADIATION; GLOBULINS; IONIZING RADIATIONS; MICROSCOPY; ORGANIC COMPOUNDS; PROTEINS; RADIATION EFFECTS; RADIATIONS; SCLEROPROTEINS
Optional Information
- Notes
- 13 refs.