Study on the inter-relationship among the changes of serum levels of leptin, insulin and glucagon in patients with DM2 complicated with hypertension
Description
Objective: To investigate the inter-relationship among the changes of serum leptin, insulin and glucagon levels in patients with type 2 diabetes mellitus (DM2) complicated with hypertension. Methods: Serum leptin, insulin and glucagon levels were, measured with RIA in 30 DM2 patients complicated with hypertension, 30 DM2 patients without hypertension and 30 controls. Results: Serum levels of leptin, insulin and glucagon in all the DM2 patients were significantly higher than those in controls (P<0.01). In addition, the serum levels in DM2 patients with hypertension were significantly higher than those in DM2 patients without hypertension (P<0.05). These levels were positively correlated with the severity of hypertension. Conclusion: The role played by leptin and glucagon in the pathogenesis of type 2 diabetes mellitns should be furthur studied. (authors)
Additional details
Publishing Information
- Journal Title
- Journal of Radioimmunology
- Journal Volume
- 19
- Journal Issue
- 3
- Journal Page Range
- p. 185-187
- ISSN
- 1008-9810
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 39096043
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BLOOD SERUM; DIABETES MELLITUS; DIAGNOSIS; GLUCAGON; HYPERTENSION; INSULIN; LEPTIN; PATHOGENESIS; PATIENTS; RADIOIMMUNOASSAY
- Descriptors DEC
- BIOASSAY; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY FLUIDS; CARDIOVASCULAR DISEASES; DIAGNOSTIC TECHNIQUES; DISEASES; ENDOCRINE DISEASES; HORMONES; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATERIALS; METABOLIC DISEASES; ORGANIC COMPOUNDS; PEPTIDE HORMONES; PEPTIDES; POLYPEPTIDES; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; SYMPTOMS; TRACER TECHNIQUES; VASCULAR DISEASES
Optional Information
- Notes
- 2 tabs., 13 refs.