Neoadjuvant chemotherapy in complex treatment of breast cancer

The paper deals with results of complex treatment of 387 patients with patients with stage 3 breast cancer assigned to either neoadjuvant chemotherapy and preoperative radiotherapy or radiation alone. A study of immediate and end results showed combination of the two modalities to be more effective then each method alone in terms of degree of regression of primary tumor and, particularly, lymph node metastases and duration of recurrence-free period