Effect of hemodialysis on left and right ventricular function

Eighteen outpatients with clonic renal failure under going hemodialysis (HD) were studied. Immediately before and after HD, the left and right ventricular function measured by electrocardiogram gated radionuclide ventriculography (RNV). By HD, body weight changed 58.6 ± 7.50 kg to 57.2 ± 6.80 kg and BUN level changed 67.9 ± 29.00 mg/dl to 37.1 ± 18.96 mg/dl and creatinine level changed 11.3 ± 3.90 mg/dl to 6.8 ± 2.48 mg/dl. Before HD, cardiac output was 8.08 ± 1.50 l/min and cardiac index was 5.00 ± 0.87 l/(min m2). Left ventricular function improved (LVEF changed 60.4 ± 6.85 % to 64.2 ± 8.7 %, LVEF/LVET changed 0.237 ± 0.048 %/ms to 0.254 ± 0.021 %/ms) between before and after HD, but there was not significant difference. Right ventricular function improved (RVEF changed 41.2 ± 8.00 % to 50.0 ± 11.96, RVEF/RVET changed 0.167 ± 0.028 %/ms to 0.209 ± 0.059 %/ms) between before and after HD, and there was significant difference (p < 0.05). (author)