Published 1990 | Version v1
Report Metadata-only

Regularities of DNA synthesis repair in populations of irradiated mammalian cells

Creators

  • 1. Akademiya Meditsinskikh Nauk SSSR, Obninsk (Russian Federation). Nauchno-Issledovatel'skij Inst. Meditsinskoj Radiologii

Description

Change in DNA synthesis rate in cell synchronous culture under radiation was shown to present result of summation of various processes (proper repair, cell transition from G1 stage into synthesis stage). Experiments with cycloheximide and actinomycin D revealed that processes resulting in DNA synthesis rate increase were inducible. Supposedly DNA synthesis in the cells following irradiation differed from DNA replication in their properties in intact cells. At this stage the problem on DNA synthesis regularities remains open. 16 refs.; 4 figs

Additional details

Additional titles

Original title (Russian)
Закономерности восстановления синтеза DNK в популяции облученных клеток млекопитающих

Publishing Information

Imprint Title
Genetic effects of charged particles
Imprint Pagination
304 p.
Journal Page Range
p. 118-126.
Report number
JINR-D--19-90-457

Conference

Title
Workshop on DNA Repair on Mutagenesis Induced by Radiation.
Dates
12-14 Jun 1990.
Place
Dubna (USSR).

INIS

Country of Publication
USSR
Country of Input or Organization
USSR
INIS RN
23071198
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; BIOSYNTHESIS; CELL CYCLE; DNA REPAIR; GAMMA RADIATION; HEATING; HELA CELLS; RESPONSE MODIFYING FACTORS; TIME DEPENDENCE; ULTRAVIOLET RADIATION
Descriptors DEC
ANIMAL CELLS; BIOLOGICAL EFFECTS; BIOLOGICAL RECOVERY; BIOLOGICAL REPAIR; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; RADIATION EFFECTS; RADIATIONS; SYNTHESIS; TUMOR CELLS

Optional Information

Notes
Imprint:Geneticheskoe dejstvie korpuskulyarnykh izluchenij.;Trudy Rabochego soveshchaniya.