Small sample Accelerator Mass Spectrometry for biomedical applications

The Accelerator Mass Spectrometry activities at Uppsala University include a group dedicated to the biomedical applications, involving natural level samples, as well as ¹⁴C-labeled substances requiring separate handling and preparation. For most applications sufficient sample amounts are available but many applications are limited to samples sizes in the μg-range. We have developed a preparation procedure for small samples biomedical applications, where a few μg C can be analyzed, albeit with compromised precision. The latest results for the small sample AMS method are shown and some of the biomedical activities at our laboratory are presented.