Determination of glomerular filtration rate in children by sequential scintigraphy with 99mTc-DTPA

The method of sequential scintigraphy of the kidneys with 99mTc-DTPA (diethylenetriaminepentaacetic acid) and subsequent determination of the glomerular filtration (GF) rate by means of a gamma camera and a computer, were applied in examining 160 children with different diseases of the kidneys and the urinary tract. By modifying an application computer program a study with quantitative evaluation of some functional parameters was designed, involving also the determination of the overall value and of separate values of GF 99mTc-CTPA according to G. Gats. The main advantages of the applied method are its noninvasiveness, speed, safety, low radiation burden, and its relatively broad applicability in diagnostic nephrological practice particularly in children. (author). 4 figs., 3 tabs., 25 refs