Frequencies of aneuploidy and dominant lethal mutations in young female mice induced by low dose γ-rays

Relationship between aneuploidy, dominant lethal mutations and doses in young feral mice induced by low dose γ-rays was examined. The results suggest that the frequencies of aneuploidy of embryos increased at 0.15 Gy, but increases at over 0.50 Gy after irradiation in groups. The frequencies of aneuploidy and dominant lethal mutations increased with increasing doses and fitted linear relationship. This dose-response relationship of trisomic was not significant. The frequency of dominant lethal mutations induced by 60Co γ irradiation is 5.59%. The effect of dominant lethal mutation is higher than that of the aneuploidy