Structure-distribution relationships of radioiodinated 1-substituted-4-phenylpiperazines

As part of the authors project to develop cerebral perfusion imaging agents they have undertaken the examination of radioiodinhe flame produce sulfur monoxide which undergoes a chemiluminescent reaction with ozone. The excited state of sulfur dioxide produced emits light with a peak wavelength of 350 nm. The USD, which has been tested in the real-time mode, has a linear response from sub part per billion by volume (ppbv) to sub part per million by volume S, and has a detection limit of about 0.13 ppbv (∼ 1 pg of S·s-1) with a time constant of 2 s. The molar response to sulfur was found to be identical for the five low molecular weight compounds tested. The USD has no interferences from water vapor or CO2. Hydrocarbon interference is minimized by adjustment of the residence time of the sample in the flame. The base line signal drift is typically undetectable over 24 h of continuous use