Published 1980 | Version v1
Journal article Metadata-only

A simple breath test for fat malabsorption in man

Creators

  • 1. Centre Hospitalier Universitaire Saint-Antoine, 75 - Paris (France)

Description

The metabolic pathway of 14C-labeled oleic acid leads to the formation and the breath excretion of 14CO2. This behavior can be used for measuring lipid absorption. The simple, accurate screening test includes the ingestion of 14C-labeled triolein and the intermittent collection of breath 14CO2 in a trapping solution. The results are strongly correlated to the measurement of fecal fat. The use of carbon-14 in man should not be restricted, provided the labeled substrates are converted into rapidly excreted metabolites

Abstract (French)

Le catabolisme de triglycerides dont les acides gras sont marques au carbone-14 aboutit a la formation de 14CO2, qui est elimine par les poumons. Ce comportement est mis a profit pour evaluer l'absorption intestinale des lipides. L'epreuve, simple et precise, consiste a faire ingerer des triglycerides marques et a recueillir le 14CO2 expire a intervalle fixe. Les resultats sont etroitement correles a ceux du dosage de la steatorrhee. La reserve qui aboutit a renoncer a utiliser le carbone-14 chez l'homme n'est pas justifiee, des lors que la metabolisation des substrats marques a pour effet une elimimation rapide du carbone-14

Additional details

Additional titles

Original title (French)
Etude des malabsorptions lipidiques chez l'homme par comptage du

Publishing Information

Journal Title
J. Fr. Biophys. Med. Nucl.
Journal Volume
4
Journal Issue
1
Series
J. Fr. Biophys. Med. Nucl.
Journal Page Range
39-43

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
11541166
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
CARBON DIOXIDE; CARBON 14 COMPOUNDS; CATABOLISM; EXHALATION; INGESTION; INTESTINAL ABSORPTION; LIPIDS; TRIOLEIN
Descriptors DEC
CARBON COMPOUNDS; CARBON OXIDES; CHALCOGENIDES; CLEARANCE; ESTERS; EXCRETION; INTAKE; METABOLISM; OILS; ORGANIC COMPOUNDS; OTHER ORGANIC COMPOUNDS; OXIDES; OXYGEN COMPOUNDS; TRIGLYCERIDES; UPTAKE