Correlative analysis of NT-proBNP and STEMI on adverse short-term outcomes in STEMI patients underwent primary PCI

Objective: To evaluate the early outcomes of patients with STEMI according to the level of serum NT-proBNP to predict whether or not appear adverse short-term outcomes in STEMI patient underwent PCI. Methods: Study patients(n = 184, mean 61.5 ± 12.6 years old, male 71.5%) with STEMI of onset < 12 h who underwent primary percutaneous coronary intervention(PCI) and who had baseline NT-proBNP serum level by ECLIA. The study subjects were divided into two groups according to the serum level of NT-proBNP. Results: Patients with NT-proBNP level > 990 pg/ml(n = 76, male 55.8%) bad left ventricle ejection fraction (LVEF)(47.7 ± 12.2% vs 53.2 ± 10.8%, P < 0.001), need longer intensive care(3.8 ± 3.6 vs 2.3 ± 2.7 days, P < 0.001), and had higher in-hospital mortality (7.2% vs 1.3%, P < 0.001) than those with NT-proBNP level ≤ 990 pg/ml(n = 108, male 75.2%). Conclusion: This experiment indicated that NT-proBNP serum level is associated with short term mortality in patients with STEMI underwent primary PCI. (authors)