Changes in DNA content, activity of acid DNA-ase and macromolecular structure of DNP during partial irradiation of rabbit's brain
Description
To study post-radiation changes of brain DNP and DNA, experiments on intact and colosotomic rabbits have been carried out by means of local X-ray irradiation of brain hemispheres. One of hemispheres has been irradiated with a single dose of 7.7-10.3 Coul/kg, the other hemisphere has been shielded. Changes in quantitative content of DNA and enzymatic activity of acidic DNA-ase by the end of irradiation are observed both in the irradiated and in the shielded hemispheres. The shielded hemisphere is characterized by the increase in the activity of acidic DNA-ase and the decrease of DNA content. Similar shifts in the irradiated hemisphere are expressed weaker. It is supposed that the increase in the activity of acidic DNA-ase in the shielded hemisphere is the physiological protective response to irradiation
Additional details
Additional titles
- Original title (Russian)
- Изменения содержания DNK, активности кислой DNK-азы и макромолекулярной структуры DNP при парциальном облучении головного мозга кроликов
Publishing Information
- Publisher
- Metsniereba.
- Imprint Place
- Tbilisi
- Imprint Title
- Radiation studies. Vol. 4
- Journal Page Range
- p. 5-19.
INIS
- Country of Publication
- USSR
- Country of Input or Organization
- USSR
- INIS RN
- 12584910
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Numerical Data
- Descriptors DEI
- BIOCHEMISTRY; BIOLOGICAL RADIATION EFFECTS; BRAIN; CATALYSIS; DINITROPHENOL; DNA; DNA-ASE; EXPERIMENTAL DATA; LOCAL IRRADIATION; METABOLISM; MOLECULAR STRUCTURE; QUANTITY RATIO; RABBITS; SHIELDING; TIME DEPENDENCE; X RADIATION
- Descriptors DEC
- ANIMALS; AROMATICS; BIOLOGICAL EFFECTS; BODY; CENTRAL NERVOUS SYSTEM; CHEMISTRY; DATA; ELECTROMAGNETIC RADIATION; ENZYMES; ESTERASES; HYDROLASES; HYDROXY COMPOUNDS; INFORMATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; NERVOUS SYSTEM; NITRO COMPOUNDS; NUCLEIC ACIDS; NUMERICAL DATA; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PHENOLS; PHOSPHATASES; RADIATION EFFECTS; RADIATIONS; VERTEBRATES
Optional Information
- Notes
- Imprint:Radiatsionnye issledovaniya. Tom 4.