Development of radiation prevention, diagnosis, and treatment platform technology for respiratory infectious diseases
Description
This study aims to develop a platform technology that can cope with the respiratory infectious disease, which is currently a social problem, using the molecular transformation technology of radiation and the radioisotope technology. First, in order to increase the efficiency of the DNA selective removal technology of radiation, it aims to develop a technology that lowers the radiation dose and minimizes the denaturation of antigens by integrating the Sensitizer technology used in cancer treatment. To this end, we will first develop a technology using the flu virus as a model and further demonstrate two respiratory infection viruses or bacteria to demonstrate the technology to develop a DNA selective removal platform technology that can be applied to various vaccines. Second, by taking advantage of the ability to control the energy of radiation, it is to develop a technology that changes the pharmacological group according to the energy level rather than chemical changes in the structure of drugs. Through prior research, we have confirmed that the structure of various new drug candidates changes according to the change of energy, and aim to develop a new drug molecular transformation platform technology that can be applied to a variety of drugs by more specific and quantifying this. . Finally, in order to apply the high diagnostic efficacy of radioisotopes to the diagnosis of infectious diseases, it takes a long time, which is a disadvantage of the existing technology, and an antibody-isotope-based virus that can easily collect and measure in real time by exhaling a sample collection method through the nasal cavity. I want to develop a diagnostic platform. If all of these technologies are developed, I think that the technology for preventing infectious diseases on a whole cycle using radiation can be completed
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Additional details
Publishing Information
- Imprint Pagination
- 92 p.
- Report number
- KAERI/RR--4693/2020
INIS
- Country of Publication
- Korea, Republic of
- Country of Input or Organization
- Korea, Republic of
- INIS RN
- 53122573
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS; S46: INSTRUMENTATION RELATED TO NUCLEAR SCIENCE AND TECHNOLOGY;
- Descriptors DEI
- ANTIBODIES; ANTIGENS; BACTERIA; DIAGNOSIS; DNA; DRUGS; EFFICIENCY; ENERGY LEVELS; INFECTIOUS DISEASES; NEOPLASMS; NOSE; RADIATION DOSES; RADIOISOTOPES; REMOVAL; SENSITIZERS; TRANSFORMATIONS; VACCINES; VIRUSES
- Descriptors DEC
- BODY; DISEASES; DOSES; FACE; HEAD; ISOTOPES; MICROORGANISMS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; PARASITES; REAGENTS; RESPIRATORY SYSTEM
Optional Information
- Notes
- 33 figs; This record replaces 53092307