Published December 2020 | Version v1
Report Open

Development of radiation prevention, diagnosis, and treatment platform technology for respiratory infectious diseases

Description

This study aims to develop a platform technology that can cope with the respiratory infectious disease, which is currently a social problem, using the molecular transformation technology of radiation and the radioisotope technology. First, in order to increase the efficiency of the DNA selective removal technology of radiation, it aims to develop a technology that lowers the radiation dose and minimizes the denaturation of antigens by integrating the Sensitizer technology used in cancer treatment. To this end, we will first develop a technology using the flu virus as a model and further demonstrate two respiratory infection viruses or bacteria to demonstrate the technology to develop a DNA selective removal platform technology that can be applied to various vaccines. Second, by taking advantage of the ability to control the energy of radiation, it is to develop a technology that changes the pharmacological group according to the energy level rather than chemical changes in the structure of drugs. Through prior research, we have confirmed that the structure of various new drug candidates changes according to the change of energy, and aim to develop a new drug molecular transformation platform technology that can be applied to a variety of drugs by more specific and quantifying this. . Finally, in order to apply the high diagnostic efficacy of radioisotopes to the diagnosis of infectious diseases, it takes a long time, which is a disadvantage of the existing technology, and an antibody-isotope-based virus that can easily collect and measure in real time by exhaling a sample collection method through the nasal cavity. I want to develop a diagnostic platform. If all of these technologies are developed, I think that the technology for preventing infectious diseases on a whole cycle using radiation can be completed

Availability note (English)

Also available from KAERI

Files

53122573.pdf

Files (4.4 MB)

Name Size Download all
md5:0fe2013d8009660fabc784d78c400cdf
4.4 MB Preview Download

Additional details

Publishing Information

Imprint Pagination
92 p.
Report number
KAERI/RR--4693/2020

Optional Information

Notes
33 figs; This record replaces 53092307