Published 1990 | Version v1
Journal article Metadata-only

131I MIBG scintigraphy in pheochromocytoma

Creators

  • 1. Ljubljana Univ. (Yugoslavia). Klinika za Nuklearno Medicino
  • 2. Ljubljana Univ. (Yugoslavia). Klinika za endokrinologijo

Description

The aim of the study was retrospective evaluation of 131I MIBG scintigraphy (SC) in patients with suspected pheochromocitoma. Results of SC, ultrasound (US) and computerized tomography (CT) were compared with histological diagnosis in 18 patients. Four hypertensive patients where pheochromocytoma was practicaly excluded on the basis of endochrinological tests and clinical course served as normals. Sensitivity of SC to detect intraadrenal tumors was 80%, CT 100% and US 92%. Overal sensitivity including 2 cases with extraadrenal tumors and 1 patient with adrenomedullary hyperplasia was for SC 83%, US 73% and CT 94%. The main advantage of SC over CT and US is in its ability to identify functional chromaffine tissue localized in intraadrenal and extraadrenal areas or metastatic spread. (author) 7 refs.; 3figs.; 1 tab

Abstract (Serbian)

Namen nashe shtudije je bil retrospektivna evalvacija scintigrafije z 131I MIBG (SC) pri pacientih s sumom na feokromocitom. Rezultate SC, ultrazvoka (UZ) in rachunalnishke tomografije (CT) smo primerjali s histoloshko diagnozo pri 18 pacientih. Pri 4 hipertenzivnih pacientih pa smo feokromocitom na podlagi endokrinoloshkih testov praktichno izkljuchili. Senzitivnost SC pri detekciji tumorjev, lokaliziranih v nadledvichni zhlezi, je bila 80%, pri CT 100% in pri UZ 92%. Skupna senzitivnost, vkljuchujoch she 2 primera tumorja lezhechega izven nadledvichnih zhlez ter 1 bolnika z hiperplazijosredice nadledvichnih zhlez, je bila pri SC 83%, pri UZ 73% in pri CT 94%. Zmozhnost ugotovljanja funkcionalnega kromafinega tkiva, lokliziranega v ali izven nadledvichnih zhlez ter v metastazah, je glavna prednost SC pred CT in UZ

Additional details

Additional titles

Original title (English)
Scintigrafija s

Publishing Information

Journal Title
Radiologia Iugoslavica
Journal Volume
24
Journal Issue
4
Series
Radiol. Iugosl.
Journal Page Range
333-336
ISSN
0485-893X
CODEN
RDIUA

INIS

Country of Publication
Slovenia
Country of Input or Organization
Yugoslavia
INIS RN
23001656
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
COMPUTERIZED TOMOGRAPHY; DIAGNOSIS; IODINE 131; LABELLED COMPOUNDS; NEOPLASMS; ORGANIC IODINE COMPOUNDS; SCINTISCANNING; SENSITIVITY ANALYSIS; ULTRASONOGRAPHY
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; COUNTING TECHNIQUES; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; RADIOISOTOPE SCANNING; RADIOISOTOPES; TOMOGRAPHY