PET timing calibration using low rank constraint

In positron emission tomography (PET), improving time resolution is essential to ensure good scanner performance. Currently, most PET scanner scintillator-based designs, and they have limitations such as a constant delay in the analog circuitry, long conductive paths, or other elements in the detectors. In this study, a novel framework based on low-rank principles is proposed for timing calibration. We follow previous framework to formulate the timing calibration process as a linear problem; the linear equations are constructed using detected coincidence events. To verify the effectiveness, Monte Carlo simulation is performed, and data are generated by the point source experiment and cylinder source experiment. The results are based on the 2D configuration, and we compare performance of the proposed method with existing methods.