Published February 2019 | Version v1
Journal article Metadata-only

Phase 2 Randomized Study of Radiation Therapy and 3-Year Androgen Deprivation With or Without Concurrent Weekly Docetaxel in High-Risk Localized Prostate Cancer Patients

Creators

  • 1. Medical Oncology Department, Hospital Universitari Vall d'Hebron, Vall d'Hebron Institute of Oncology, Barcelona (Spain)
  • 2. Medical Oncology Department, Parc Taulí Hospital Universitari, Institut d'Investigació i Innovació Parc Taulí I3PT, Universitat Autònoma de Barcelona, Sabadell (Spain)
  • 3. Medical Oncology Department, Hospital Althaia Manresa, Barcelona (Spain)
  • 4. Medical Oncology Department, Institut Català d'Oncologia, Hospital Germans Trias i Pujol, Badalona, Barcelona (Spain)
  • 5. Medical Oncology Department, Hospital del Mar, IMIM, Barcelona (Spain)

Description

Docetaxel improves survival in patients with metastatic prostate cancer. This randomized phase 2 trial aimed to assess the activity of weekly docetaxel with radiation therapy (RT) plus androgen deprivation in patients with high-risk localized prostate cancer. The study examined the benefit of 9 weekly docetaxel administrations to RT plus 3 years of luteinizing hormone-releasing hormone analogues.

Additional details

Identifiers

DOI
10.1016/j.ijrobp.2018.10.005;
PII
S0360301618338562;

Publishing Information

Journal Title
International Journal of Radiation Oncology, Biology and Physics
Journal Volume
103
Journal Issue
2
Journal Page Range
p. 344-352
ISSN
0360-3016
CODEN
IOBPD3

INIS

Country of Publication
United States
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
55060917
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ANDROGENS; HEALTH HAZARDS; LIBERINS; LUTEINIZING HORMONE; METASTASES; NEOPLASMS; PATIENTS; PROSTATE; RADIOTHERAPY
Descriptors DEC
ANDROSTANES; BODY; CARBOHYDRATES; DISEASES; GLANDS; GLYCOPROTEINS; GONADOTROPINS; HAZARDS; HORMONES; MALE GENITALS; MEDICINE; NUCLEAR MEDICINE; ORGANIC COMPOUNDS; ORGANS; PEPTIDE HORMONES; PITUITARY HORMONES; PROTEINS; RADIOLOGY; SACCHARIDES; STEROID HORMONES; STEROIDS; THERAPY

Optional Information

Copyright
Copyright (c) 2018 Elsevier Inc. All rights reserved.