Modified extended tanh-function method and nonlinear dynamics of microtubules

Highlights: ► An improved model of nonlinear dynamics of microtubules is explained. ► A basic mathematical tool is modified extended tanh-function method. ► The dynamics of microtubules is explained by kink solitons. ► This is related to some biological phenomena. - Abstract: We here present a model of nonlinear dynamics of microtubules (MT) in the context of modified extended tanh-function (METHF) method. We rely on the ferroelectric model of MTs published earlier by Satarić et al. where the motion of MT subunits is reduced to a single longitudinal degree of freedom per dimer. It is shown that such nonlinear model can lead to existence of kink solitons moving along the MTs. An analytical solution of the basic equation, describing MT dynamics, was compared with the numerical one and a perfect agreement was demonstrated. It is now clearer how the values of the basic parameters of the model, proportional to viscosity and internal electric field, impact MT dynamics. Finally, we offer a possible scenario of how living cells utilize these kinks as signaling tools for regulation of cellular traffic as well as MT depolymerisation.