Raman and CRDS isotopic resolution spectroscopy for biomedicine applications

SRS-sensor was developed for measuring absolute amount ratios of ¹³C/¹²C isotopes for medical application. Measuring absolute amount ratios of ¹³C/¹²C isotopes allows detection of Helicobacter pylori for medical diagnostics of human health. SRS method is used to measure the amount of carbon dioxide isotopes in exhaled air to detect Helicobacter pylori. This is used to determine influence of the bacterium on the occurrence of gastritis, gastric and duodenal ulcers. This paper includes methods and metrological characteristics for measuring isotopes ratios. (paper)