Published April 1980
| Version v1
Journal article
The effects of dexamethasone (DXM) and vitamin A on the growth and metamorphosis of gamma irradiated, thyroxine induced Bufo melanostictus tadpoles
Description
This study deals with the effects of vitamin A and dexamethasone (DXM) on the metamorphosis of irradiated tadpoles. Results indicate that hypervitaminosis A depresses the metamorphosing action of thyroxine for several days. On the contrary, dexamethasone accelerates the action of exogenous thyroxine on tadpoles. Thus present data suggest that DXM supresses STH synthesis and promotes TSH secretion. Moreover, muscle appears to be its target tissue and DXM seems to promote the proteolytic digestion of the larval tail. (author)
Additional details
Publishing Information
- Journal Title
- Radiobiol. Radiother.
- Journal Volume
- 21
- Journal Issue
- 2
- Series
- Radiobiol. Radiother.
- Journal Page Range
- 156-161
- ISSN
- 0033-8184
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- German Democratic Republic
- INIS RN
- 11570062
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- AMPHIBIANS; ANIMAL GROWTH; DEXAMETHASONE; GAMMA RADIATION; LARVAE; METAMORPHOSIS; STH; THYROXINE; TIME DEPENDENCE; TSH; VITAMIN A
- Descriptors DEC
- ADRENAL HORMONES; AMINO ACIDS; ANIMALS; AQUATIC ORGANISMS; CARBOXYLIC ACIDS; CORTICOSTEROIDS; ELECTROMAGNETIC RADIATION; GLUCOCORTICOIDS; GROWTH; HORMONES; HYDROXY COMPOUNDS; IONIZING RADIATIONS; KETONES; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; PEPTIDE HORMONES; PITUITARY HORMONES; PREGNANES; RADIATIONS; STEROID HORMONES; STEROIDS; THYROID HORMONES; VERTEBRATES; VITAMINS