Evaluation of the therapeutic effect of arterial PVA embolization for mid and advanced pulmonary carcinoma

Objective: To explore the therapeutic effect of arterial PVA perfusion embolization in treating mid and advanced pulmonary carcinoma. Methods: Thirty-one patients with pulmonary carcinoma in the mid or late stage diagnosed pathologically underwent selective angiographic studies of the bronchial arteries and intercostal arteries to provide information of the hypervascular feeding vessels, and then performed the perfusion with 5-FU, THP, DDP; followed by PVA grain embolization under fluoroscopic control. Results: Abnormal tumor feeding vessels of pulmonary carcinoma were found deriving from bromehial arteries in 21 cases, and from intercostal arteries in 10. After arterial infusion of chemotherapy combined with embolization of PVA, alleviation of clinical symptoms was observed in all 31 cases (100%)without severe complication. The total effectiveness (CR plus PR) reached 80.6%(25/31). Conclusions: Arterial embolization of PVA is safe, effective with less complication for treatment of mid or advanced pulmonary carcinoma. (authors)