Radionuclide scanning of the spleen

In order to cut down the time needed for the preparation of the thermally damaged erythrocytes, the effect of heat was combined with the use of a higher concentration of ACD. Heating of the 51Cr tagged red cells was performed in a water bath, at 500C for 15 minutes, in the presence of ACD in the ratio of one ml ACD for every 3 ml blood. Using this technique, the obtained splenic scans in 20 normal individuals were excellent in quality. In the posterior view, the spleen was oval with an oblique long axis in 65% of the cases and transverse long axis in another 15%. In the remaining 20% the spleen was globular. The average measurements of the spleen were 10.5 x 7.1 cm, with a circumference of 29.8 cm. By planimetry, the surface area of the spleen averaged (59 +- 12.4) cm2 (Mean +- 1 S.D.). In the lateral projection, the surface area of the splenic scan was larger by an average of 40% than the picture obtained through the posterior approach in all the six examined subjects. (orig.)