Published February 2013 | Version v1
Journal article

Immunochromatographic lateral flow strip for on-site detection of bisphenol A

  • 1. School of Biotechnology and Food Engineering, Hefei University of Technology, Hefei, 230009 (China)
  • 2. School of Food Science and Technology, Jiangnan University, Wuxi, 210004 (China)
  • 3. Jiangsu Entry-exit Inspection and Quarantine Bureau, Nanjing, 200002 (China)

Description

We have developed a lateral flow assay (LFA) for the detection of bisphenol A (BPA) in water samples. Antibody against BPA was labeled with gold nanoparticles, and these conjugates were used as the recognition probes for the construction of an LFA strip. The diameter of the gold nanoparticles, the amount of antibody, the pH of the buffer, and the categories of the conjugation pad were optimized. The resulting method has a (visual) detection limit of 5 ppb, and of 0.92 ppb if used in combination with professional software. This LFA displays excellent specificity and was applied to spiked water samples with satisfactory results. (author)

Additional details

Identifiers

Publishing Information

Journal Title
Microchimica Acta (Online)
Journal Volume
180
Journal Issue
3-4
Journal Page Range
p. 279-285
ISSN
1436-5073

INIS

Country of Publication
Austria
Country of Input or Organization
Austria
INIS RN
44052688
Subject category
S77: NANOSCIENCE AND NANOTECHNOLOGY; S54: ENVIRONMENTAL SCIENCES;
Descriptors DEI
ANTIBODIES; BUFFERS; COMPUTER CODES; FOOD; GOLD; NANOSTRUCTURES; PARTICLES; PH VALUE; PROBES; SAFETY; SENSITIVITY; SPECIFICITY; WATER
Descriptors DEC
ELEMENTS; HYDROGEN COMPOUNDS; METALS; OXYGEN COMPOUNDS; TRANSITION ELEMENTS