Use of non-structural proteins to FMDV to assess antibodies in vaccinated and infected cattle in Peru

The identification of animals that have been infected with FMDV is very important for the control measures of the disease, because the animals frequently become carriers and can be the cause of new outbreaks. In countries were vaccination is applied it is recognised that there is the necessity to use tests that can differentiate the antibodies resulted from the vaccine and the antibodies from infection. In recent years tests have been developed that identify antibodies against virus-specific proteins present only in infected animals, being the non-structural protein 2C and non-structural 3ABC polyprotein the most studied. The work made under the CRP can be divided into three phases. (1) Examination of a set of tests provided up to 2002; (2) Examination of tests provided from 2002 to present and; (3) Studies on post vaccinated animal to examine whether antibodies to NSP are produced. (author)