Published December 2008 | Version v1
Journal article

Fetal MR imaging of atelosteogenesis type II (AO-II)

  • 1. Hospital for Sick Children, Department of Diagnostic Imaging, Toronto (Canada)
  • 2. Mount Sinai Hospital, Department of Pathology, Toronto (Canada)
  • 3. University of Freiburg, Institute for Human Genetics and Center for Pediatrics and Adolescent Medicine, Freiburg (Germany)
  • 4. Mount Sinai Hospital, Department of Medical Imaging, Toronto (Canada)
  • 5. St. Michael's Hospital, Department of Obstetrics and Gynecology, Toronto (Canada)
  • 6. Mount Sinai Hospital, The Prenatal Diagnosis and Medical Genetics Program, Toronto (Canada)

Description

The diastrophic dysplasia family of osteochondrodysplasias comprises a spectrum of skeletal diseases characterized by abnormal growth and remodelling of cartilage and bone. They are caused by mutations in the diastrophic dysplasia sulfate transporter (DTDST) gene. Different defects in this gene product give rise to the variety of phenotypes based on the level of residual transport capacity. We reported a case of a fetus with this spectrum, evaluated and diagnosed with fetal MRI. (orig.)

Availability note (English)

Available from: http://dx.doi.org/10.1007/s00247-008-0974-y

Additional details

Identifiers

Publishing Information

Journal Title
Pediatric Radiology
Journal Volume
38
Journal Issue
12
Journal Page Range
p. 1345-1349
ISSN
0301-0449
CODEN
PDRYA5

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
40000278
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BONE TISSUES; DIAGNOSIS; GROWTH; IMAGES; NMR IMAGING
Descriptors DEC
ANIMAL TISSUES; BODY; CONNECTIVE TISSUE; DIAGNOSTIC TECHNIQUES