Published 1983
| Version v1
Book
Tritiation of unsaturated tricyclic antidepressants for radioimmunoassay
Description
A rapid and convenient method to obtain specific an high activity tritium labelling of tricyclic antidepressants which have a double bond, is described. The procedure is based on the halogenation of the active benzylic positions of the unlabelled material and the selective catalytic removal of the halogen atom by tritium in the presence of a base which inhibits the attack on the olefin bond
Additional details
Publishing Information
- Publisher
- Pergamon Press.
- Imprint Place
- Paris (France)
- ISBN
- 0-08-026405-0
- Imprint Title
- Nuclear medicine and biology advances
- Imprint Pagination
- 542 p.
- Journal Page Range
- v. 4 p. 3350-3352.
Conference
- Title
- 3. World congress of nuclear medicine and biology.
- Dates
- 29 Aug - 2 Sep 1982.
- Place
- Paris (France).
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 16026953
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- ANTIDEPRESSANTS; DEHALOGENATION; HALOGENATION; LABELLING; RADIOIMMUNOASSAY; TRITIUM COMPOUNDS
- Descriptors DEC
- CENTRAL NERVOUS SYSTEM AGENTS; CHEMICAL REACTIONS; DRUGS; HYDROGEN COMPOUNDS; ISOTOPE APPLICATIONS; PSYCHOTROPIC DRUGS; TRACER TECHNIQUES