Published April 1993 | Version v1
Journal article

Visualization of ultraviolet light-induced thymine dimers in DNA by immunoelectron microscopy

  • 1. Nagasaki Univ. (Japan). School of Medicine

Description

To see the damage of DNA due to ultraviolet-B more distinctly, immunoelectron microscopic studies using a monoclonal antibody against cyclobutane-type thymine dimers were performed. As a result, we could detect the existence of thymine dimers on human genomic DNA and pUC18 plasmid DNA visually. This technique can be useful to locate the photoproducts formed on DNA. (Author)

Additional details

Publishing Information

Journal Title
Photochemistry and Photobiology
Journal Volume
57
Journal Issue
4
Journal Page Range
p. 752-754.
ISSN
0031-8655
CODEN
PHCBAP