Measurement uncertainty for QC/QA applied to the chemical analysis

The expression of uncertainty applied to the chemical analysis is highly recommended with increasing demands upon the systematic Quality Assurance and Control (QA/QC) with ISO 17025. For the quantification of quality source, 7 major common sources of uncertainty, normally contributing to the quality of the chemical analysis, were selected form QA/QC literatures of chemical analysis. They were classified into repeatability, drift, uncertainty in standards, linearity of calibration, homogeneity, stability of sample, and matrix effect. And the quantification of the sources by means of measurement uncertainty was proposed as a prerequisite steps for QA/QC. Examples applied to the quantification procedures of modeling, combination and expression of standard uncertainty for the 7 major common sources were presented as a reference guide for QA/QC in chemical analysis