Published May 2019
| Version v1
Journal article
Three-Fraction Accelerated Partial Breast Irradiation (APBI) Delivered With Brachytherapy Applicators Is Feasible and Safe: First Results From the TRIUMPH-T Trial
Creators
- 1. Memorial Sloan Kettering Cancer Center, New York, New York (United States)
- 2. Michigan Healthcare Professionals, 21st Century Oncology, Farmington Hills (United States)
- 3. Beaumont Health System, Royal Oak (United States)
- 4. University of California San Diego/Moores Cancer Center, La Jolla (United States)
- 5. Huntsman Cancer Institute, Salt Lake City (United States)
- 6. Bryn Mawr Hospital, Bryn Mawr (United States)
Description
Shorter courses of accelerated partial-breast irradiation delivered as single-fraction intraoperative therapy are now offered as an alternative to 4 to 6 weeks of whole-breast irradiation after lumpectomy. However, this approach has potential shortcomings in patient selection and target volume definition and in dosimetric, radiobiological, and logistical issues. We designed a prospective, phase 2, multi-institution clinical trial to study 2- or 3-day accelerated partial breast irradiation delivered with brachytherapy applicators.
Additional details
Identifiers
- DOI
- 10.1016/j.ijrobp.2018.12.050;
- PII
- S0360301618342329;
Publishing Information
- Journal Title
- International Journal of Radiation Oncology, Biology and Physics
- Journal Volume
- 104
- Journal Issue
- 1
- Journal Page Range
- p. 67-74
- ISSN
- 0360-3016
- CODEN
- IOBPD3
INIS
- Country of Publication
- United States
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 55057219
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BRACHYTHERAPY; CLINICAL TRIALS; DESIGN; IRRADIATION; MAMMARY GLANDS; PATIENTS
- Descriptors DEC
- BODY; GLANDS; MEDICINE; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; RADIOTHERAPY; TESTING; THERAPY
Optional Information
- Copyright
- Copyright (c) 2019 Elsevier Inc. All rights reserved.