Formation of microcapsule from high methoxyl pectins and whey lactoglobulin

The process of microencapsulation of model drug through complex formation between whey lactoglobulin concentrate and different high methoxyl pectins from apples and citrus in the oil/water interface were investigated. There are optimum conditions for obtaining stable emulsions by changing the ionic strength of the system, capable of forming a solid layer at the oil/water interface were studied. It is shown that the emulsion system formed by apple pectin has maximum particle number, higher drug loading efficiency in comparison with the citrus pectin. Delivery systems in the form of emulsion microparticles have demonstrated the ability to efficiently encapsulate the model drug-piroxicam, which can be widely used in the development of injectable and aerosol delivery systems. (author)