Monte Carlo estimation of patient effective dose in diagnostics procedures using 131I
Creators
- 1. Faculty of Technical Sciences, University of Novi Sad, 21000 Novi Sad, Trg Dositeja Obradovica 6 (Serbia)
- 2. VINCA Institute of Nuclear Sciences, 11001 Belgrade, PB522 (Serbia)
Description
Therapeutic or diagnostic radiopharmaceutical capsule containing Na131I stays in stomach for 15 minutes before the absorption starts, long enough to make possible risky exposure. During the oral application it is reasonable to measure effective dose in stomach. Direct measurements of organ doses are not possible so there is a strong recommendation to estimate them by calculation. The main goal is the 131I risk assessment. Monte Carlo code MCNP4b was used to model the transport of gamma and beta particles emitted by radionuclide 131I considered as a point source at the bottom of the stomach. Absorbed energy per unit transformation in stomach and surrounding organs has been calculated. The dose equivalents in these organs have been calculated in aim to determine the effective doses using appropriate tissue weighting factor values. Obtained results had not significant importance for radiation protection but they were important for establishment of new calibration procedures as a part of QA and QC programs in radiopharmaceuticals production and control.
Availability note (English)
Available from http://dx.doi.org/10.1088/1742-6596/238/1/012054Additional details
Identifiers
Publishing Information
- Journal Title
- Journal of Physics. Conference Series (Online)
- Journal Volume
- 238
- Journal Issue
- 1
- Journal Page Range
- [6 p.]
- ISSN
- 1742-6596
Conference
- Title
- 13. IMEKO (International Measurement Confederation) TC1-TC7 joint symposium
- Dates
- 1-3 Sep 2010
- Place
- London (United Kingdom)
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 42046838
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- ABSORPTION; BETA PARTICLES; CALIBRATION; COMPUTERIZED SIMULATION; DOSE EQUIVALENTS; IODINE 131; MONTE CARLO METHOD; PATIENTS; POINT SOURCES; RADIATION DOSES; RADIATION PROTECTION; RADIOPHARMACEUTICALS; RISK ASSESSMENT; STOMACH; TRANSFORMATIONS
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CALCULATION METHODS; CHARGED PARTICLES; DAYS LIVING RADIOISOTOPES; DIGESTIVE SYSTEM; DOSES; DRUGS; GASTROINTESTINAL TRACT; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; IONIZING RADIATIONS; ISOTOPES; LABELLED COMPOUNDS; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIATION SOURCES; RADIATIONS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SIMULATION; SORPTION