Reactions of 2,4-dialkoxy-1,2,4-azadiphosphetidines with some electrophilic reagents

The alkylation, acylation, phosphorylation, and bromination of 2,4-dialkoxy-1,2,4-azadiphosphetidines go by the Arbuzov-reaction scheme with the formation of the corresponding 1,2,4-azadiphosphetidines containing one or two 4-coordinate phosphorus atoms in the molecule. The structures of the new 1,2,4-azadiphosphetidines obtained were investigated with the aid of the 1H, 31P, and 13C NMR spectra, assignments were made for the signals of the cis and trans isomers of these compounds, and some of their geometric parameters were determined. The Arbuzov reactions of 2,4-dialkoxy-1,2,4-azadiphosphetidines with methyl iodide, bromine, and some acyl halides go with change in the proportions of the cis and trans isomers in the reaction products in comparison with the original azadiphosphetidines, which is the result of the change in the configuration of one of the phosphorus atoms in the ring