The role of radon in changing the concentration of oxidative stress predictors involved in the pathogenesis of epilepsy

To clarify the mechanism of action of radon on antioxidative processes, future research is required, but based on the results of experiments received by means of a photometric analytical system FRAS-5, dedicated solely to the global assessment of oxidative stress in biological systems by enabling the measurement of pro-oxidant status in plasma samples by means of d-ROMs (reactive oxygen metabolites), fast test and of anti-oxidant status in plasma by means of PAF (Plasma Antioxidant Fragments) test, as well as measurement of OBRI (Oxidation Balance Risk Index) and OSI (Oxidation Index), we can conclude that the obtained results have shown that inhalation of Tskaltubo water develops a hormesis that causes the brain to changes in all named oxidative stress predictors. These predictors should be involved in the regulation of oxidative-degenerative processes, which are clinically manifested in the reduction of epileptic convulsions. Inhalation of Tskaltubo water may be considered as a method of treatment with anticonvulsant effect confirmed by experimental studies. (author)