Published July 30, 2013 | Version v1
Journal article

Comparison between whole-body MRI and Fluorine-18-Fluorodeoxyglucose PET or PET/CT in oncology: a systematic review

  • 1. Institute of Radiology, Università Cattolica del Sacro Cuore, Rome (Italy)
  • 2. Institute of Nuclear Medicine, Università Cattolica del Sacro Cuore, Rome (Italy)

Description

The aim of the article is to systematically review published data about the comparison between positron emission tomography (PET) or PET/computed tomography (PET/CT) using Fluorine-18-Fluorodeoxyglucose (FDG) and whole-body magnetic resonance imaging (WB-MRI) in patients with different tumours. A comprehensive literature search of studies published in PubMed/MEDLINE, Scopus and Embase databases through April 2012 and regarding the comparison between FDG-PET or PET/CT and WB-MRI in patients with various tumours was carried out. Forty-four articles comprising 2287 patients were retrieved in full-text version, included and discussed in this systematic review. Several articles evaluated mixed tumours with both diagnostic methods. Concerning the specific tumour types, more evidence exists for lymphomas, bone tumours, head and neck tumours and lung tumours, whereas there is less evidence for other tumour types. Overall, based on the literature findings, WB-MRI seems to be a valid alternative method compared to PET/CT in oncology. Further larger prospective studies and in particular cost-effectiveness analysis comparing these two whole-body imaging techniques are needed to better assess the role of WB-MRI compared to FDG-PET or PET/CT in specific tumour types

Availability note (English)

Available from http://dx.doi.org/10.2478/raon-2013-0007; Available from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3794875

Additional details

Publishing Information

Journal Title
Radiology and Oncology
Journal Volume
47
Journal Issue
3
Journal Page Range
p. 206-218
ISSN
1318-2099

Optional Information

Copyright
Copyright (c) by Association of Radiology & Oncology
Notes
PMCID: PMC3794875; PMID: 24133384; PUBLISHER-ID: rado-47-03-206; OAI: oai:pubmedcentral.nih.gov:3794875; This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).