Published July 1976 | Version v1
Journal article Metadata-only

The influence of experimental conditions on the efficiency of labeling human serum albumin with sup(99m)Tc, using Sn(II) as the reductant

Creators

  • 1. Rijksuniversiteit Utrecht (Netherlands). Analytisch Chemisch Lab.

Description

The influence of the pH and of the albumin and Sn(II) concentrations on the efficiency of labeling human serum albumin with sup(99m)Tc has been investigated by means of a 4 x 3 x 3 factorial design, with duplication. The equation, describing the response surface as a function of the three investigated variables, has been derived. This response equation is used to find the optimum labeling conditions and in a discussion of the chemistry of the labeling. (author)

Additional details

Identifiers

DOI
10.1016/0020-708x(76)90087-9;

Publishing Information

Journal Title
The International Journal of Applied Radiation and Isotopes
Journal Volume
27
Journal Issue
7
Series
Int. J. Appl. Radiat. Isot.
Journal Page Range
351-356
ISSN
0020-708X

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
7274905
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
ALBUMINS; BLOOD SERUM; EFFICIENCY; LABELLING; MAN; PH VALUE; REDUCTION; RESPONSE FUNCTIONS; STATISTICAL MODELS; TECHNETIUM 99; TIN COMPLEXES
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; CHEMICAL REACTIONS; COMPLEXES; FUNCTIONS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MATHEMATICAL MODELS; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; PRIMATES; PROTEINS; RADIOISOTOPES; TECHNETIUM ISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES

Optional Information

Notes
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