Published 1987
| Version v1
Journal article
Radioprotection of peripheral blood cells with a combination of hydroxytryptophan and a thiol compound in mice
- 1. Delhi Univ. (India). Inst. of Nuclear Medicine and Allied Sciences
- 2. Delhi Univ. (India). Radiation Biochemistry Div.
Description
Radiation induced changes in peripheral blood cells were studied in male Swiss albino mice after 4 Gy and 10 Gy whole body gamma irradiation with and without pretreatment with 2-amino-ethylisothiuronium bromide hydrobromide (AET) or with a combination of 5-hydroxy-L-tryptophan (5-HTP) and AET. Combination of 5-HTP with AET or AET alone in a high dose achieved excellent protection against both 4 Gy and 10 Gy whole body irradiation as regards peripheral blood cell counts. (orig.)
Additional details
Publishing Information
- Journal Title
- Acta Oncol. (Stockh.)
- Journal Volume
- 26
- Journal Issue
- 3
- Series
- Acta Oncol. (Stockh.).
- Journal Page Range
- 229-232
- CODEN
- ACTOE
INIS
- Country of Publication
- Sweden
- Country of Input or Organization
- Sweden
- INIS RN
- 19027082
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- AET; BIOLOGICAL RADIATION EFFECTS; BLOOD CELLS; EFFICIENCY; GAMMA RADIATION; HYDROXYTRYPTOPHAN; MICE; RADIOPROTECTIVE SUBSTANCES; WHOLE-BODY IRRADIATION
- Descriptors DEC
- AMINES; AMINO ACIDS; ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BODY FLUIDS; CARBONIC ACID DERIVATIVES; CARBOXYLIC ACIDS; DRUGS; ELECTROMAGNETIC RADIATION; EXTERNAL IRRADIATION; HYDROXY ACIDS; IONIZING RADIATIONS; IRRADIATION; MAMMALS; MATERIALS; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC SULFUR COMPOUNDS; RADIATION EFFECTS; RADIATIONS; RESPONSE MODIFYING FACTORS; RODENTS; THIOUREAS; VERTEBRATES