Clinical results of maxillary sinus squamous cell carcinoma

The clinical findings of 43 cases with maxillary sinus squamous cell carcinoma treated between 1994 and 2007 were analyzed retrospectively. The patients ranged from 39-81 years of age (median of 63 years) and consisted of 34 men and nine women. In terms of the clinical T factor for these patients according to the American Joint Committee on Cancer (AJCC) classification (1997), there were three cases with T2, 12 cases with T3, 12, and 28 cases with T4. Three patients were diagnosed with lymph node metastases. The median follow-up time was 52 months (range of 6-162 months). From 1994 to 2004, accelerated hyperfractionated radiotherapy combined with low-dose carboplatin (CBDCA) infusion was used preoperatively, and intensity-modulated radiotherapy (IMRT) combined with high-dose cisplatin (CDDP) infusion chemotherapy was used from 2005 to 2007. The five-year overall survival rate (OS), five-year disease-free survival rate (DFS), and five-year local control rate (LC) of all patients were 80%, 72.6%, and 72.7%, respectively. The IMRT combined with high-dose CDDP infusion chemotherapy group had better OS than the other group, but it was not statistically significant. (author)