Published October 1986 | Version v1
Journal article Metadata-only

Positron-emitting analogs of SCH 23390 for the study of dopamine D1 receptors

Creators

  • 1. Chicago Univ., IL (USA). Dept. of Radiology
  • 2. Chicago Univ., IL (USA). Dept. of Pharamacological and Physiological Science
  • 3. Argonne National Lab., IL (USA)

Description

With the discovery of benzazepines as selective D1 ligands either as agonists or antagonists, studies on the function of D1 receptors and the functional significance of multiple classes of DA receptors are actively being pursued in several laboratories. We have prepared two positron emitting analogs of SCH 23390 in order to assess its potential as imaging agents in positron emission tomography (PET). (author)

Additional details

Publishing Information

Journal Title
J. Labelled Compd. Radiopharm.
Journal Volume
23
Journal Issue
10-12
Series
J. Labelled Compd. Radiopharm.
Journal Page Range
1403-1404
ISSN
0362-4803
CODEN
JLCRD

Conference

Title
6. international symposium on radiopharmaceutical chemistry.
Dates
29 Jun - 3 Jul 1986.
Place
Boston, MA (USA).

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
18082060
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Resource subtype / Literary indicator
Conference
Descriptors DEI
AROMATICS; BRAIN; BROMINE 75; BROMINE 76; CARBON 11; CHEMICAL PREPARATION; DOPAMINE; LABELLING; MONKEYS; ORGANIC NITROGEN COMPOUNDS; POSITRON COMPUTED TOMOGRAPHY; RADIOPHARMACEUTICALS; RECEPTORS; TISSUE DISTRIBUTION
Descriptors DEC
AMINES; ANIMALS; AUTONOMIC NERVOUS SYSTEM AGENT; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; BROMINE ISOTOPES; CARBON ISOTOPES; CARDIOTONICS; CARDIOVASCULAR AGENTS; CENTRAL NERVOUS SYSTEM; COMPUTERIZED TOMOGRAPHY; DISTRIBUTION; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EMISSION COMPUTED TOMOGRAPHY; EVEN-ODD NUCLEI; HOURS LIVING RADIOISOTOPES; HYDROXY COMPOUNDS; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MAMMALS; MATERIALS; MINUTES LIVING RADIOISOTOPES; NERVOUS SYSTEM; NEUROREGULATORS; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANS; PHENOLS; POLYPHENOLS; PRIMATES; RADIOACTIVE MATERIALS; RADIOISOTOPES; SECONDS LIVING RADIOISOTOPES; STEROIDS; SYMPATHOMIMETICS; SYNTHESIS; TOMOGRAPHY; VERTEBRATES