Dose-response curve slope improvement and result reproducibility of ferrous-sulphate-doped gels analysed by NMR imaging
- 1. Milan Univ. (Italy). Ist. di Fisica
- 2. Istituto Nazionale per lo Studio e la Cura dei Tumori, Milan (Italy)
Description
Ferrous sulphate gel analysed by relaxation time measurements with NMR imaging is considered a useful dosimeter for 3D determinations of absorbed dose. A protocol for the gel preparation with agarose SeaPlaque that leads to a dosimeter with very high dose sensitivity is described. The dose-response curve slope is about 0.2 s-1 Gy-1 and the G factor turns out to be ∼ 185 ions per 100 eV of absorbed energy. A method for making the measurements and analysing the results that brings about good result reproducibility is suggested. A thorough experimental study of the dependence of the dosimeter response on the elapsed time from preparation to irradiation and from irradiation to NMR measurement has revealed good reproducibility. The above characteristic of the gel system is very interesting, because it shows the possibility of utilizing the dosimeter for absolute dose determinations with satisfactory reliability. (Author)
Additional details
Publishing Information
- Journal Title
- Physics in Medicine and Biology
- Journal Volume
- 39
- Journal Issue
- 4
- Journal Page Range
- p. 703-717.
- ISSN
- 0031-9155
- CODEN
- PHMBA7
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 25049830
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S61: RADIATION PROTECTION AND DOSIMETRY;
- Descriptors DEI
- CHEMICAL DOSEMETERS; GELS; IRON COMPOUNDS; NMR IMAGING; PERFORMANCE TESTING; RADIATION DOSES; RELAXATION TIME; SENSITIVITY; SULFATES
- Descriptors DEC
- COLLOIDS; DIAGNOSTIC TECHNIQUES; DISPERSIONS; DOSEMETERS; MEASURING INSTRUMENTS; OXYGEN COMPOUNDS; SULFUR COMPOUNDS; TESTING; TRANSITION ELEMENT COMPOUNDS