Published 1983 | Version v1
Journal article Metadata-only

11C-methiodide quinuclidinyl benzilate, a muscarinic antagonist for in vivo studies of myocardial muscarinic receptors

Creators

  • 1. CEA, 91 - Orsay (France). Service Hospitalier Frederic Joliot

Description

A method for labelling MQNB (methiodide quinuclidinyl benzilate) with carbon-11 using 11C-methyl iodide is reported. Injectable labelled product (100 mCi; max. 200 mCi) radiochemically and chemically pure is obtained in a 30 minute synthesis time with a specific activity of 1 Ci/μmmol, (max. 2.3 Ci/μmol). (author)

Additional details

Publishing Information

Journal Title
J. Radioanal. Chem.
Journal Volume
76
Journal Issue
2
Series
J. Radioanal. Chem.
Journal Page Range
305-309
ISSN
0134-0719

INIS

Country of Publication
Hungary
Country of Input or Organization
Hungary
INIS RN
14782679
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
CARBON 11; CHEMICAL PREPARATION; FLOWSHEETS; HETEROCYCLIC COMPOUNDS; IN VIVO; INJECTION; LABELLING; LIQUID COLUMN CHROMATOGRAPHY; METHYL IODIDE; METHYLATION; MYOCARDIUM; RADIOPHARMACEUTICALS; RECEPTORS; TOMOGRAPHY
Descriptors DEC
BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; CARBON ISOTOPES; CARDIOVASCULAR SYSTEM; CHEMICAL REACTIONS; CHROMATOGRAPHY; DIAGNOSTIC TECHNIQUES; DIAGRAMS; DRUGS; EVEN-ODD NUCLEI; HEART; INFORMATION; INTAKE; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; MINUTES LIVING RADIOISOTOPES; MUSCLES; NUCLEI; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANS; RADIOACTIVE MATERIALS; RADIOISOTOPES; SEPARATION PROCESSES; SYNTHESIS

Optional Information

Notes
13 refs.