Published May 1998
| Version v1
Journal article
Imagery: the ways of antisense oligonucleotide
Creators
Description
The positrons emission tomography (PET) is a medical imagery technology used in fundamental research and in pharmacology. This technology allows to follow the ''progress'' in all (or in part of) the human body, of molecules which are labelled by a radioisotope. A team of CEA and INSERM researchers has just developed a universal labelling method with fluorine 18 which works for all the genetic sequences. These molecules (antisense oligonucleotides) are formed by a succession of twenty complementary bases of RNA. It is an important technical advance which could play a key role in the promotion of antisense oligonucleotide as of medicine. (O.M.)
Additional details
Additional titles
- Original title (French)
- Imagerie: les chemins de l'antisens
Publishing Information
- Journal Title
- Defis du CEA
- Journal Issue
- no.67
- Journal Page Range
- p. 6
- ISSN
- 1163-619X
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 30008475
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- FLUORINE 18; LABELLED COMPOUNDS; POSITRON COMPUTED TOMOGRAPHY; RNA
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; COMPUTERIZED TOMOGRAPHY; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LIGHT NUCLEI; NANOSEC LIVING RADIOISOTOPES; NUCLEI; NUCLEIC ACIDS; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; RADIOISOTOPES; TOMOGRAPHY