Published 1978 | Version v1
Report Restricted

Removal of uv-induced pyrimidine dimers from the replicated and unreplicated DNA of human fibroblasts

Creators

Description

Excision repair in uv irradiated human fibroblasts has been examined in portions of DNA replicating after irradiation versus those remaining unreplicated. Two approaches, one using a uv-endonuclease to estimate pyrimidine dimers remaining in DNA, the other using density labeling to measure excision resynthesis, indicate that the extent of repair is the same for both replicated and unreplicated DNA

Availability note (English)

MF available from INIS under the Report Number; Available from NTIS., PC A02/MF A01.

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Additional details

Publishing Information

Imprint Pagination
4 p.
Report number
CONF-780226--1

Conference

Title
Symposium on DNA repair mechanisms.
Dates
19 - 24 Feb 1978.
Place
Keystone, CO, USA.

INIS

Country of Publication
United States
Country of Input or Organization
United States
INIS RN
9395015
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Conference
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL REPAIR; DNA; FIBROBLASTS; NUCLEASES; PHOTOCHEMISTRY; PYRIMIDINES; ULTRAVIOLET RADIATION
Descriptors DEC
ANIMAL CELLS; AZINES; BIOLOGICAL EFFECTS; BIOLOGICAL RECOVERY; CHEMISTRY; CONNECTIVE TISSUE CELLS; ELECTROMAGNETIC RADIATION; ENZYMES; HETEROCYCLIC COMPOUNDS; NUCLEIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; PHOSPHOTRANSFERASES; RADIATION EFFECTS; RADIATIONS; SOMATIC CELLS; TRANSFERASES