Published November 1982
| Version v1
Journal article
Multilamellar DSPC liposomes: vesicles with improved stability
Description
Liposomes are useful in vivo radiopharmaceuticals as they can be of variable size and entrap any water or lipid soluble radiochemical. Leakage of the radionuclide must be minimised and the lipsome must not be able to migrate from the target. Liposomes of distearoylphosphotidyl choline were prepared and labelled with 99Tc. Their stability, in vitro, was determined by dialysis and biodistribution in mice and rabbits investigated after intravenous injection. (U.K.)
Additional details
Publishing Information
- Journal Title
- J. Labelled Compd. Radiopharm.
- Journal Volume
- 19
- Journal Issue
- 11-12
- Series
- J. Labelled Compd. Radiopharm.
- Journal Page Range
- 1469-1471
Conference
- Title
- 4. International symposium on radiopharmaceutical chemistry.
- Dates
- 23-27 Aug 1982.
- Place
- Juelich (Germany, F.R.).
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 14783689
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BIOLOGICAL LOCALIZATION; DIALYSIS; INTRAVENOUS INJECTION; LIPOSOMES; LIVER; LUNGS; MICE; PERTECHNETATES; PHOSPHOLIPIDS; RABBITS; RADIOACTIVITY; RADIOPHARMACEUTICALS; RADIOTHERAPY; SPLEEN; TECHNETIUM 99
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CELL CONSTITUENTS; DIGESTIVE SYSTEM; DRUGS; ESTERS; GLANDS; HOURS LIVING RADIOISOTOPES; INJECTION; INTAKE; INTERMEDIATE MASS NUCLEI; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIPIDS; MAMMALS; MATERIALS; MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC PHOSPHORUS COMPOUNDS; ORGANS; OXYGEN COMPOUNDS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RESPIRATORY SYSTEM; RODENTS; SEPARATION PROCESSES; TECHNETIUM COMPOUNDS; TECHNETIUM ISOTOPES; THERAPY; TRANSITION ELEMENT COMPOUNDS; VERTEBRATES; YEARS LIVING RADIOISOTOPES