Study of the cyclotron production of 172Lu. An excellent radiotracer
Creators
- 1. Nuclear Science and Technology Research Institute, Karaj, Tehran (Iran, Islamic Republic of). Agricultural, Medical and Industrial Research School
- 2. Islamic Azad University, Tehran (Iran, Islamic Republic of). Faculty of Engineering, Research and Science Branch
Description
172Lu due to its suitable (T1/2 = 6.7 days) and high detection sensitivity, is used as a radiotracer in different fields. 172Lu appears to be suitable as a long-lived rare-earth tracer for compound labelling and biodistribution studies. In the present study, excitation functions via 172Yb(p,n)172Lu, natYb(p,xn)172Lu, 172Yb(d,2n)172Lu and natYb(d,xn)172Lu reactions were calculated by ALICE/91, ALICE/ASH and TALYS-1.2 codes. Deposition of natYb2O3 on Cu substrate was carried out via sedimentation method for the production of 172Lu. Cementation separation process and liquid-liquid extraction (LLX) of no-carrier-added (nca) radiolutetium from irradiated ytterbium(III)oxide target hydrochloric solution was described using Na(Hg) amalgam, α-hydroxyisobutyric acid (α-HIB) and di-(2-ethylhexyl)phosphoric acid (HDEHP). (author)
Additional details
Publishing Information
- Journal Title
- Journal of Radioanalytical and Nuclear Chemistry
- Journal Volume
- 286
- Journal Issue
- 1
- Journal Page Range
- p. 259-263
- ISSN
- 0236-5731
- CODEN
- JRNCDM
INIS
- Country of Publication
- Hungary
- Country of Input or Organization
- Hungary
- INIS RN
- 41121043
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
- Descriptors DEI
- CYCLOTRONS; LABELLING; LUTETIUM 172; MERCURY ALLOYS; SEDIMENTATION; TRACER TECHNIQUES
- Descriptors DEC
- ACCELERATORS; ALLOYS; BETA DECAY RADIOISOTOPES; CYCLIC ACCELERATORS; DAYS LIVING RADIOISOTOPES; ELECTRON CAPTURE RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; LUTETIUM ISOTOPES; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; RADIOISOTOPES; RARE EARTH NUCLEI
Optional Information
- Notes
- 27 refs.