A neural lens for super-resolution biological imaging
Creators
- 1. Optoelectronics Research Centre, University of Southampton, Southampton, SO17 1BJ (United Kingdom)
- 2. Department of Physics and Astronomy, University of Southampton, Southampton, SO17 1BJ (United Kingdom)
- 3. Faculty of Medicine, University of Southampton, Southampton, SO17 1BJ (United Kingdom)
Description
Visualizing structures smaller than the eye can see has been a driving force in scientific research since the invention of the optical microscope. Here, we use a network of neural networks to create a neural lens that has the ability to transform 20× optical microscope images into a resolution comparable to a 1500× scanning electron microscope image. In addition to magnification, the neural lens simultaneously identifies the types of objects present, and hence can label, colour-enhance and remove specific types of objects in the magnified image. The neural lens was used for the imaging of Iva xanthiifolia and Galanthus pollen grains, showing the potential for low cost, non-destructive, high-resolution microscopy with automatic image processing. (paper)
Availability note (English)
Available from http://dx.doi.org/10.1088/2399-6528/ab267dAdditional details
Identifiers
Publishing Information
- Journal Title
- Journal of Physics Communications
- Journal Volume
- 3
- Journal Issue
- 6
- Journal Page Range
- [7 p.]
- ISSN
- 2399-6528
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 52021051
- Subject category
- S60: APPLIED LIFE SCIENCES; S97: MATHEMATICAL METHODS AND COMPUTING;
- Descriptors DEI
- COLOR; IMAGE PROCESSING; IMAGES; LENSES; NEURAL NETWORKS; OPTICAL MICROSCOPES; POLLEN; SCANNING ELECTRON MICROSCOPY
- Descriptors DEC
- ELECTRON MICROSCOPY; GAMETES; GERM CELLS; MICROSCOPES; MICROSCOPY; OPTICAL PROPERTIES; ORGANOLEPTIC PROPERTIES; PHYSICAL PROPERTIES; PROCESSING