Published February 1984
| Version v1
Journal article
Use of ascorbic acid in the 51Cr labelling of mouse fibrosarcoma cells
- 1. Cancer Research Inst., Bombay (India). Biophysics Div.
Description
We have studied and discussed the significance of the use of ascorbic acid in 51Cr labelling of cells. The following two advantages seem credible if cells (mouse fibrosarcoma) in culture are incubated for about 2 h in a medium containing Na251CrO4 and then ascorbic acid is added to the medium and incubation continued for ten more minutes: (a) the natural intracellular conversion of Cr6+ to Cr3+ appears to be aided. (b) the incorporation of chromium by cells is higher. (orig.)
Additional details
Publishing Information
- Journal Title
- Radiat. Environ. Biophys.
- Journal Volume
- 23
- Journal Issue
- 1
- Series
- CODEN: REBPA.;Radiat. Environ. Biophys.
- Journal Page Range
- 75-78
- ISSN
- 0301-634X
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 15021223
- Subject category
- S60: APPLIED LIFE SCIENCES; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- ASCORBIC ACID; CHROMIUM 51; FIBROSARCOMAS; LABELLING; MICE; RADIOPHARMACEUTICALS; TISSUE CULTURES; TUMOR CELLS; UPTAKE
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BETA DECAY RADIOISOTOPES; CHROMIUM ISOTOPES; DISEASES; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EVEN-ODD NUCLEI; INTERMEDIATE MASS NUCLEI; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; MATERIALS; NEOPLASMS; NUCLEI; RADIOACTIVE MATERIALS; RADIOISOTOPES; RODENTS; SARCOMAS; VERTEBRATES; VITAMINS