Published February 18, 1987 | Version v1
Journal article

17O NMR spectroscopy: torsion angle relationships in aryl carboxylic esters, acids, and amides

Description

17O NMR spectroscopic data (natural abundance in acetonitrile at 750C) were obtained for the following series of electronically similar, sterically hindered compounds: aromatic methyl esters, aromatic carboxylic acids, and aromatic amides. Torsional angles were calculated by the molecular mechanics (MM2) method. Linear regression analysis of the estimated torsion angles and the 17O chemical shift data for each series yielded the following results (series, slope δ/degree, correlation coefficient): esters (C=O), 0.70, 0.997; esters (-0-), 0.43, 0.992; acids (-CO2H), 0.56, 0.994; amides (C=O), 0.84, 0.942; N,N-dimethylamides (C=O), 0.6, 0.991. The results are discussed in terms of minimization of repulsive van der Waals interactions by rotation of the functional group out of the plane of the aromatic ring

Additional details

Publishing Information

Journal Title
J. Am. Chem. Soc.
Journal Volume
109
Journal Issue
4
Series
J. Am. Chem. Soc.
Journal Page Range
1059-1062
ISSN
0002-7863
CODEN
JACSA